Tuesday, August 11, 2009

Smoking may speed progress of multiple sclerosis


Dr. Alberto Ascherio of the Harvard School of Public Health in Boston and his colleagues also found that smokers with MS is more likely that the progressive form of the disease when symptoms become worse, instead of relapsing-remitting form in which a person has MS symptoms intermittent injection.

"Most of the adverse effects were observed in current smokers, which in any way is good news because it suggests that smoking cessation can help Ascherio told Reuters Health.

People who smoke are known to be an increased risk of MS, but research on smoking affects the course of the disease have conflicting results, he and his colleagues note. They followed 1,465 MS patients, 17.5% of these were active smokers, with an average of just over three years to investigate.

Of 891 patients, the team came after the deadline for determining the degree of progression from one form of the disease to another, as their 72 Member States to be relapsing-remitting form: 20 of 154 smokers, 20 of 237 ex -- - smokers and 32 500 non-smokers.

This meant that smokers were 2.4 times as likely as non-smokers have primary progressive MS, who had relapsing-remitting disease were 2.5 times more likely than nonsmokers to develop secondary progressive MS during follow-up period. The study is beginning, smokers had more disability, more severe disease and atrophy in their heads. Over time, they also showed a sharp increase in the total amount of damaged brain tissue and their degree of atrophy of the brains.

The mechanism that cigarette smoking may be worse, MS is not clear Ascherio said. Smoking is associated with a number of other autoimmune diseases such as rheumatoid arthritis, he noted, while others are not so accustomed to the effects on the immune system may be a factor, another possibility could be that cigarette smoke is toxic to the nervous system.

There is no documented risk factors for progression of MS is that the patient can do something with Ascherio noted.

"Although a causal link has yet been proven, says he and his colleagues write" These results suggest that patients with MS who quit smoking, not only the risk of smoking diseases, but also curb the development of MS.

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